🧠 New Research Alert: Collaborative Breakthrough in Glioma Therapy

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We’re excited to share a newly published research article resulting from a collaboration between the labs of Dr. Maria G Castro and Dr. Anna Schwendeman!

HDL Nanodiscs Loaded with Liver X Receptor Agonist Decreases Tumor Burden and Mediates Long-term Survival in Mouse Glioma Model

Troy A Halseth, Anzar A Mujeeb, Lisha Liu, Kaushik Banerjee, Nigel Lang, Todd Hollon, Minzhi Yu, Mark Vander Roest, Ling Mei, Hongliang He, Maya Sheth, Maria G Castro, Anna Schwendeman

Published in Small, 2025

This study highlights the development of HDL nanodiscs as an innovative delivery platform for Liver X Receptor (LXR) agonists, demonstrating significant reduction in tumor burden and improved long-term survival in a preclinical glioma model. This work represents a promising advancement in nanomedicine-based strategies for brain cancer treatment.

👉 Read the full article here: https://pubmed.ncbi.nlm.nih.gov/40249282/