Category: Article
🧠New Research Alert: Collaborative Breakthrough in Glioma Therapy
April 23, 2025A recent collaborative study from the Castro and Schwendeman labs showcases the therapeutic potential of HDL nanodiscs delivering LXR agonists, demonstrating reduced tumor burden and long-term survival benefits in a mouse glioma model. Published in Small (2025).
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Upcoming Publication (In Press): Peripheral blood mononuclear cell (PBMC)- based functional evaluation of human T cell response to suppressive cells and immune-oncology therapeutics
April 16, 2025This new chapter presents in vitro assays to evaluate T cell function under immunosuppressive conditions, offering insights into how immunotherapies can restore anti-tumor T cell responses.
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New Publication Alert: Local controlled release of stabilized monoclonal antibodies
April 16, 2025A new biodegradable delivery system enables long-term, localized release of monoclonal antibodies, showing promising results in preclinical models of wet AMD and glioblastoma. This platform could expand antibody-based therapies to hard-to-reach tissues.
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Commentary: The discrete charm of oncolytic viruses: Toward the finish line
April 16, 2025An expert commentary in Cancer Cell highlights emerging advancements in oncolytic virus therapies, including engineered viral platforms and delivery strategies showing promise against aggressive cancers such as brain tumors.
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